2024 Myotubularin-related protein

Myotubularin-related protein

Author: ffnq

August undefined, 2024

Myotubularin domain represents a region within eukaryotic myotubularin-related proteins that is sometimes found with the GRAM domain InterPro: IPR004182. Myotubularin is a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5) … See more MTM1; MTMR1; MTMR10; MTMR11; MTMR12; MTMR2; MTMR3; MTMR4; MTMR6; MTMR7; MTMR8; MTMR9; SBF1; SBF2; See more • PDOC51339 - Myotubularin phosphatase domain in PROSITE See more WebJun 10, 2024 · In this context, we identified 76 kDa myotubularin-related protein 7 (MTMR7), a member of the myotubularin (MTM) family of lipid phosphatases, as a novel interaction …

MTMR3 myotubularin related protein 3 [ (human)]

WebOct 20, 2024 · MTMR2:myotubularin related protein 2 [Gene - OMIM - HGNC] Variant type: single nucleotide variant Cytogenetic location: 11q21 Genomic location: Chr11: 95845106 (on Assembly GRCh38) Chr11: 95578270 (on Assembly GRCh37) Preferred name: NM_016156.6(MTMR2):c.1233G>A (p.Thr411=) Other names: cornelian asset managers ltd

Human myotubularin-related protein 9 regulates ER-to-Golgi …

WebAug 23, 2013 · From a database screen for protein sequences similar to human myotubularin (), which is mutated in a form of centronuclear myopathy (CNMX; 310400), Tosch et al. (2006) identified a novel protein, MTMR14, with high homology to Drosophila egg-derived tyrosine phosphatase (EDTP).The authors called this protein hJUMPY … WebFeb 20, 2024 · Myotubularin-related protein 14 (MTMR14) is a member of the myotubularin (MTM)-related protein family, which is involved in apoptosis, aging, inflammation, and … WebRegulation of phosphatidylinositol phosphates plays a crucial role in signal transduction, membrane trafficking or autophagy.Members of the myotubularin family of lipid phosphatases contribute to phosphoinositide metabolism by counteracting the activity of phosphoinositide kinases. The mechanisms determining their subcellular localization and … cornelian bay cemetery and crematorium

Myotubularin-related protein 14 suppresses cardiac …

8897 - Gene ResultMTMR3 myotubularin related protein 3 [ (human)]

WebMyotubularin-related protein 2: mTOR: Mechanistic target of rapamycin: MYRF: Myelin regulatory factor: NG2: Chondroitin sulfate proteoglycan neuron-glia antigen 2: Nkx2.2: NK2 homeobox 2: NOTCH1: Notch receptor 1: NPC: Niemann–Pick Type C disease: NPC1: NPC intracellular cholesterol transporter 1: NRG1: Neuregulin-1: WebMyotubularin is thought to be involved in the development and maintenance of muscle cells. This enzyme acts as a phosphatase, which means that it removes clusters of oxygen and phosphorus atoms (phosphate groups) from other molecules. fang wei wei towel wrapWebMay 1, 2012 · Myotubularin proteins can be grouped into subfamilies based on homology. Closely related MTMR6, MTMR7, and MTMR8 comprise such a subfamily, and MTMR9 is the sole member of another subfamily. Previous studies have shown that MTMR9 binds to MTMR6 ( 24) and to MTMR7 ( 25 ). cornelia mensdorff pouilly

"WebMTMR8 belongs to the myotubularin family of inositol polyphosphate 3-phosphatases. Myotubularins have unique functions within cells by regulating a specific pool of dephosphorylating phosphatidylinositol 3-phosphate (PtdIns (3)P) and phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5)P2) (summary by Zou et al., 2012 ). " - Myotubularin-related protein

Myotubularin-related protein

WebOct 31, 2024 · MTMR14 (myotubularin-related protein 14) is a novel phosphoinositide phosphatase that has a variety of biological functions and is involved in diverse biological processes. However, the role of MTMR14 in vascular biology remains unclear. Herein, we addressed the role of MTMR14 in neointima formation and vascular smooth muscle cell … WebMay 18, 2024 · By searching an EST database for sequences related to the myotubularin gene (MTM1; 300415), Laporte et al. (1998) identified a partial MTMR6 (myotubularin-related protein-6) cDNA and cDNAs encoding 3 other …

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WebMTMR2 myotubularin related protein 2 Gene ID: 8898, updated on 29-Mar-2024 Gene type: protein coding ... This gene is a member of the myotubularin family of phosphoinositide … WebMyotubularin-related proteins constitute one of the largest and most highly conserved protein tyrosine phosphatase (PTP) subfamilies in eukaryotes [14, 19]. The MTM family …

WebCMT4B1 is caused by mutations in the gene encoding myotubularin-related protein 2 (MTMR2; 11q22), involved in polyphosphoinositide signaling. Transmitted in an autosomal recessive manner. [from SNOMEDCT_US] Available tests. 57 … WebMar 9, 2024 · We recently identified myotubularin related protein-2 (Mtmr2), a phosphoinositide (PI) phosphatase, in the native Piezo2 interactome of murine dorsal root ganglia (DRG). Here, we demonstrate that Mtmr2 attenuates Piezo2-mediated rapidly adapting mechanically activated (RA-MA) currents.

WebMar 29, 2024 · myotubularin related protein 11. Gene ID: 10903, updated on 8-Dec-2024. Gene type: protein coding. Also known as: CRA. See all available tests in GTR for this … WebNov 15, 2011 · Myotubularin (MTM1; 300415) and myotubularin-related proteins are dual-specificity phosphatases. Several myotubularin-related proteins (e.g., MTMR1, 300171) …

WebJan 15, 2011 · MTMs are known to play a fundamental role in human physiology as gene mutations can give rise to X-linked myotubular myopathy or Charcot-Marie-Tooth disease, which manifest in skeletal muscle or in peripheral neurons respectively.

WebSep 29, 2006 · 300171 - MYOTUBULARIN-RELATED PROTEIN 1; MTMR1 - MTMR1 Buj-Bello et al. (2002) determined that the 2 main MTMR1 protein muscular isoforms, like myotubularin, efficiently dephosphorylate PI(3)P in vitro. The authors found a striking reduction in the level of the muscle-specific isoform and the appearance of an abnormal … cornelian bay cemetery hobartWebOct 6, 2003 · Myotubularins (MTMs) represent one of the largest and most conserved families of dual-specific protein tyrosine phosphatase-like enzymes ( 1 ). To date, 14 MTM genes have been identified, three of which have been associated with human diseases. fang where the wild things areWebFeb 20, 2024 · Myotubularin-related protein 14 (MTMR14) is a member of the myotubularin (MTM)-related protein family, which is involved in apoptosis, aging, inflammation, and autophagy. However, its exact... cornelian bay boathouse kioskWebJun 10, 2024 · Phosphoinositide phosphatase Myotubularin-Related-Protein-7 (MTMR7) was identified as cytosolic interaction partner of PPARγ. Synthetic peptides were designed resembling the regulatory... cornelian bay boathouse cafeWebJan 15, 2011 · The MTM (myotubularin)/MTMR (myotubularin-related) protein family is comprised of 15 lipid phosphatases, of which nine members are catalytically active. fangwire pathfinderWebThe protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol (3)-phosphate and phosphatidylinositol (3,5)-biphosphate in … fang wild boarWebMTMR8 belongs to the myotubularin family of inositol polyphosphate 3-phosphatases. Myotubularins have unique functions within cells by regulating a specific pool of … cornelian bay cemetery and crematorium hobart